The transmission to Ōno domain constitutes one example of vaccine sharing between domains within Echizen province. 

the lords connected 

The physicians participated in a network. The two leaders of Ōno's vaccination program, Tsuchida Ryūwan and Hayashi Unkei, were both domain physicians who had studied in Osaka with two prestigious scholars of Dutch medicine, Ogata Kōan and Kō Ryōsai. They had been sent to Osaka in 1845 by their lord. Unlike Fukui's lord, Ōno's lord Doi Toshitada had a long-standing interest in Dutch Learning and occasionally invited prominent scholars such as Sugita Seikei, Koseki San’ei, and Takami Senseki to lecture for him at his mansion in Edo. Toshitada encouraged Dutch Learning among his vassals, and probably also had a strong personal motive for bringing the smallpox vaccine to Ōno as quickly as possible. In the spring of 1849, smallpox claimed the life of his infant son and heir, only a few months before the vaccine reached Japan’s shores. Though neither Tsuchida Ryūwan and Hayashi Unkei had studied with Kasahara Hakuō, their study in Osaka connected them to the same extended medical lineages as Hakuō and Hakuō's teacher Hino Teisai.

News of the importation of the vaccine quickly reached Toshitada. In the 10th month of 1849, before the vaccine had even arrived in Fukui, he entrusted Tsuchida Ryūwan with some funds from his own purse to bring the vaccine to Ōno. Early in 1850, domain physician Hayashi Unkei as well as town doctor Nakamura Taisuke went to Fukui to formally ask Kasahara Hakuō for a transmission. Like all the other physicians who received transmissions from Hakuō, they had to sign the vaccinators’ oath. The extant copy of the oath shows both men’s signatures under the date of 2/14 [insert image].

While in Fukui, Unkei and Taisuke vaccinated the “small child of a tobacco dealer” and brought the toddler back to Ōno. After seven days they transferred the lymph to three more children (Iwaji, p. 105; check other) and from there to another three and so on to spread the supply.

On one hand, Toshitada took advantage the domain-crossing networks of his doctors. On the other hand, he made smallpox vaccinations part of a much narrower political agenda that was focused on the exclusive needs of his domain. 
Mercantilist logic: make the vaccine benefit the population within one's borders   an autonomous economic space
 In 1842 Toshitada launched a major domain reform with the main goal of improving the domain’s budgetary situation. During the Tenpō famine in the 1830s, the domain had lost at least 4,900 people (out of a population of approximately 29,000), and it seems that Toshitada saw vaccinations as a way to boost the economy by increasing the population. One of the earliest domain edicts advertising the benefits of the vaccine began with the statement that in “Holland,” not a single life had been lost to smallpox since the commencement of the vaccinations, and the population was increasing every year. In 1858, the government claimed that in the past seven or eight years the domain population had increased by 2,000 thanks to vaccinations.